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Detection of inflammatory cell function using (13)C magnetic resonance spectroscopy of hyperpolarized [6-(13)C]-arginine

Myeloid-derived suppressor cells (MDSCs) are highly prevalent inflammatory cells that play a key role in tumor development and are considered therapeutic targets. MDSCs promote tumor growth by blocking T-cell-mediated anti-tumoral immune response through depletion of arginine that is essential for T...

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Detalles Bibliográficos
Autores principales: Najac, Chloé, Chaumeil, Myriam M., Kohanbash, Gary, Guglielmetti, Caroline, Gordon, Jeremy W., Okada, Hideho, Ronen, Sabrina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979036/
https://www.ncbi.nlm.nih.gov/pubmed/27507680
http://dx.doi.org/10.1038/srep31397