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Development and utility of an in vitro, fluorescence-based assay for the discovery of novel compounds against dengue 2 viral protease

BACKGROUND: Dengue disease is one of the most significant vector-borne illnesses in the world. The emergence and re-emergence of dengue infections in many parts of the world affect millions annually and continue to burden public health systems especially in low-income populations. Advances in dengue...

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Detalles Bibliográficos
Autores principales: Ulanday, Gianne Eduard L., Okamoto, Kenta, Morita, Kouichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979183/
https://www.ncbi.nlm.nih.gov/pubmed/27551237
http://dx.doi.org/10.1186/s41182-016-0025-6