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Design and application of a target capture sequencing of exons and conserved non-coding sequences for the rat

BACKGROUND: Target capture sequencing is an efficient approach to directly identify the causative mutations of genetic disorders. To apply this strategy to laboratory rats exhibiting various phenotypes, we developed a novel target capture probe set, TargetEC (target capture for exons and conserved n...

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Detalles Bibliográficos
Autores principales: Yoshihara, Minako, Saito, Daisuke, Sato, Tetsuya, Ohara, Osamu, Kuramoto, Takashi, Suyama, Mikita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979189/
https://www.ncbi.nlm.nih.gov/pubmed/27506932
http://dx.doi.org/10.1186/s12864-016-2975-9