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Design and application of a target capture sequencing of exons and conserved non-coding sequences for the rat
BACKGROUND: Target capture sequencing is an efficient approach to directly identify the causative mutations of genetic disorders. To apply this strategy to laboratory rats exhibiting various phenotypes, we developed a novel target capture probe set, TargetEC (target capture for exons and conserved n...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979189/ https://www.ncbi.nlm.nih.gov/pubmed/27506932 http://dx.doi.org/10.1186/s12864-016-2975-9 |