Class I HDAC inhibitor mocetinostat induces apoptosis by activation of miR-31 expression and suppression of E2F6

The class I selective inhibitor of the histone deacetylases, mocetinostat, has promising antitumor activities in both preclinical studies and the clinical trials. To understand how mocetinostat induces apoptosis, we examined the effects of mocetinostat on miR-31, a proapoptotic microRNA that was pre...

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Detalles Bibliográficos
Autores principales: Zhang, Q, Sun, M, Zhou, S, Guo, B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979414/
https://www.ncbi.nlm.nih.gov/pubmed/27551526
http://dx.doi.org/10.1038/cddiscovery.2016.36

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979414/
https://www.ncbi.nlm.nih.gov/pubmed/27551526
http://dx.doi.org/10.1038/cddiscovery.2016.36

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