Novel β-carbolines against colorectal cancer cell growth via inhibition of Wnt/β-catenin signaling

Wnt signaling pathway is aberrantly activated in a variety of cancers, especially in colorectal cancer (CRC), because of mutations in the genes encoding adenomatous polyposis coli (APC), β-catenin and Axin. Small-molecule antagonists of Wnt/β-catenin signaling are attractive candidates for developin...

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Detalles Bibliográficos
Autores principales: Li, X, Bai, B, Liu, L, Ma, P, Kong, L, Yan, J, Zhang, J, Ye, Z, Zhou, H, Mao, B, Zhu, H, Li, Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979417/
https://www.ncbi.nlm.nih.gov/pubmed/27551464
http://dx.doi.org/10.1038/cddiscovery.2015.33

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979417/
https://www.ncbi.nlm.nih.gov/pubmed/27551464
http://dx.doi.org/10.1038/cddiscovery.2015.33

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