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Novel β-carbolines against colorectal cancer cell growth via inhibition of Wnt/β-catenin signaling
Wnt signaling pathway is aberrantly activated in a variety of cancers, especially in colorectal cancer (CRC), because of mutations in the genes encoding adenomatous polyposis coli (APC), β-catenin and Axin. Small-molecule antagonists of Wnt/β-catenin signaling are attractive candidates for developin...
Autores principales: | Li, X, Bai, B, Liu, L, Ma, P, Kong, L, Yan, J, Zhang, J, Ye, Z, Zhou, H, Mao, B, Zhu, H, Li, Y |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979417/ https://www.ncbi.nlm.nih.gov/pubmed/27551464 http://dx.doi.org/10.1038/cddiscovery.2015.33 |
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