Mitochondrial oligomers boost glycolysis in cancer stem cells to facilitate blebbishield-mediated transformation after apoptosis

Apoptosis culminates in secondary necrosis due to lack of ATP. Cancer stem cells form spheres after apoptosis by evoking the blebbishield emergency program. Hence, determining how blebbishields avoid secondary necrosis is crucial. Here we demonstrate that N-Myc and VEGFR2 control transformation from...

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Detalles Bibliográficos
Autores principales: Jinesh, GG, Molina, JR, Huang, L, Laing, NM, Mills, GB, Bar-Eli, M, Kamat, AM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979437/
https://www.ncbi.nlm.nih.gov/pubmed/27551498
http://dx.doi.org/10.1038/cddiscovery.2016.3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979437/
https://www.ncbi.nlm.nih.gov/pubmed/27551498
http://dx.doi.org/10.1038/cddiscovery.2016.3

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