The H1047R point mutation in p110 alpha changes the morphology of human colon HCT116 cancer cells

The class IA phosphatidylinositol 3-kinases (PI3K) is involved in controlling changes in cell morphology, which is a highly coordinated cellular event. This event is powered by actin filament polymerization and remodeling. The gain-of-function mutations in the catalytic subunit of p110α of class IA...

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Detalles Bibliográficos
Autores principales: Wan, G, Pehlke, C, Pepermans, R, Cannon, JL, Lidke, D, Rajput, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979441/
https://www.ncbi.nlm.nih.gov/pubmed/27551473
http://dx.doi.org/10.1038/cddiscovery.2015.44

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979441/
https://www.ncbi.nlm.nih.gov/pubmed/27551473
http://dx.doi.org/10.1038/cddiscovery.2015.44

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