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The H1047R point mutation in p110 alpha changes the morphology of human colon HCT116 cancer cells
The class IA phosphatidylinositol 3-kinases (PI3K) is involved in controlling changes in cell morphology, which is a highly coordinated cellular event. This event is powered by actin filament polymerization and remodeling. The gain-of-function mutations in the catalytic subunit of p110α of class IA...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979441/ https://www.ncbi.nlm.nih.gov/pubmed/27551473 http://dx.doi.org/10.1038/cddiscovery.2015.44 |