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Cigarette smoke-induced cell death of a spermatocyte cell line can be prevented by inactivating the Aryl hydrocarbon receptor

Cigarette smoke exposure causes germ cell death during spermatogenesis. Our earlier studies demonstrated that cigarette smoke condensate (CSC) causes spermatocyte cell death in vivo and growth arrest of the mouse spermatocyte cell line (GC-2spd(ts)) in vitro via the aryl hydrocarbon receptor (AHR)....

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Detalles Bibliográficos
Autores principales: Esakky, P, Hansen, D A, Drury, A M, Cusumano, A, Moley, K H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979462/
https://www.ncbi.nlm.nih.gov/pubmed/27551479
http://dx.doi.org/10.1038/cddiscovery.2015.50