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Questions and controversies in innate immune research: what is the physiological role of NLRP3?
The NLRP3 inflammasome is a key component of the innate immune system that induces pro-inflammatory cytokine production and cell death. Although NLRP3 is activated by many pathogens, it only appears to be critical for host defense for a limited number of specific infections. NLRP3 is however strongl...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979470/ https://www.ncbi.nlm.nih.gov/pubmed/27551512 http://dx.doi.org/10.1038/cddiscovery.2016.19 |