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Macrophage-mediated chronic lymphocytic leukemia cell survival is independent of APRIL signaling

Survival of chronic lymphocytic leukemia (CLL) cells is mainly driven by interactions within the lymph node (LN) microenvironment with bystander cells such as T cells or cells from the monocytic lineage. Although the survival effect by T cells is largely governed by the TNFR ligand family member CD4...

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Detalles Bibliográficos
Autores principales: van Attekum, MHA, Terpstra, S, Reinen, E, Kater, AP, Eldering, E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979474/
https://www.ncbi.nlm.nih.gov/pubmed/27551513
http://dx.doi.org/10.1038/cddiscovery.2016.20