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Stereospecific induction of apoptosis in tumor cells via endogenous C(16)-ceramide and distinct transcripts

Concentration and distribution of individual endogenous ceramide species is crucial for apoptosis induction in response to various stimuli. Exogenous ceramide analogs induce apoptosis and can in turn modify the composition/concentrations of endogenous ceramide species and associated signaling. In th...

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Detalles Bibliográficos
Autores principales: Blaess, M, Le, HP, Claus, RA, Kohl, M, Deigner, H-P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979478/
https://www.ncbi.nlm.nih.gov/pubmed/27551447
http://dx.doi.org/10.1038/cddiscovery.2015.13