SAG-UPS attenuates proapoptotic SARM and Noxa to confer survival advantage to early hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is a deadly cancer because of its commonly late diagnosis and limited treatment options. SAG (sensitive to apoptosis gene)-dependent UPS (ubiquitin–proteasome system) is a key switch between immune-mediated apoptosis and overactivation-mediated protumorigenesis, prompt...

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Detalles Bibliográficos
Autores principales: Chang, S C, Choo, W Q W, Toh, H C, Ding, J L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979479/
https://www.ncbi.nlm.nih.gov/pubmed/27551463
http://dx.doi.org/10.1038/cddiscovery.2015.32

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979479/
https://www.ncbi.nlm.nih.gov/pubmed/27551463
http://dx.doi.org/10.1038/cddiscovery.2015.32

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