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The interplay of autophagy and β-Catenin signaling regulates differentiation in acute myeloid leukemia

The major feature of leukemic cells is an arrest of differentiation accompanied by highly active proliferation. In many subtypes of acute myeloid leukemia, these features are mediated by the aberrant Wnt/β-Catenin pathway. In our study, we established the lectin LecB as inducer of the differentiatio...

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Detalles Bibliográficos
Autores principales: Kühn, K, Cott, C, Bohler, S, Aigal, S, Zheng, S, Villringer, S, Imberty, A, Claudinon, J, Römer, W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979480/
https://www.ncbi.nlm.nih.gov/pubmed/27551462
http://dx.doi.org/10.1038/cddiscovery.2015.31