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The interplay of autophagy and β-Catenin signaling regulates differentiation in acute myeloid leukemia
The major feature of leukemic cells is an arrest of differentiation accompanied by highly active proliferation. In many subtypes of acute myeloid leukemia, these features are mediated by the aberrant Wnt/β-Catenin pathway. In our study, we established the lectin LecB as inducer of the differentiatio...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979480/ https://www.ncbi.nlm.nih.gov/pubmed/27551462 http://dx.doi.org/10.1038/cddiscovery.2015.31 |