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Induction and inhibition of the pan-nuclear gamma-H2AX response in resting human peripheral blood lymphocytes after X-ray irradiation

Human peripheral blood lymphocytes (HPBLs) are one of the most sensitive cells to ionizing radiation (IR) in the human body, and IR-induced DNA damage and functional impairment of HPBLs are the adverse consequences of IR accidents and major side effects of radiotherapy. Phosphorylated H2AX (γH2AX) i...

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Detalles Bibliográficos
Autores principales: Ding, D, Zhang, Y, Wang, J, Zhang, X, Gao, Y, Yin, L, Li, Q, Li, J, Chen, H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979483/
https://www.ncbi.nlm.nih.gov/pubmed/27551505
http://dx.doi.org/10.1038/cddiscovery.2016.11