Cytotoxic L-amino-acid oxidases from Amanita phalloides and Clitocybe geotropa induce caspase-dependent apoptosis

L-amino-acid oxidases (LAO) purified from fungi induce cell death in various mammalian cells including human tumor cell lines. The mechanism, however, remains poorly understood. In this study, we aimed to define a precise mechanism of cell death induced in Jurkat and MCF7 cancer cell lines by ApLAO...

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Detalles Bibliográficos
Autores principales: Pišlar, A, Sabotič, J, Šlenc, J, Brzin, J, Kos, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979486/
https://www.ncbi.nlm.nih.gov/pubmed/27551514
http://dx.doi.org/10.1038/cddiscovery.2016.21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979486/
https://www.ncbi.nlm.nih.gov/pubmed/27551514
http://dx.doi.org/10.1038/cddiscovery.2016.21

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