Hypoxia and classical activation limits Mycobacterium tuberculosis survival by Akt-dependent glycolytic shift in macrophages

Cellular reactive oxygen species (ROS) is a major antibacterial defense mechanism used by macrophages upon activation. Exposure of Mycobacterium tuberculosis (Mtb)-infected macrophages to hypoxia is known to compromise the survival of the pathogen. Here we report that the hypoxia-induced control of...

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Detalles Bibliográficos
Autores principales: Matta, S K, Kumar, D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979487/
https://www.ncbi.nlm.nih.gov/pubmed/27551515
http://dx.doi.org/10.1038/cddiscovery.2016.22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979487/
https://www.ncbi.nlm.nih.gov/pubmed/27551515
http://dx.doi.org/10.1038/cddiscovery.2016.22

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