Defining the minimal peptide sequence of the ING1b tumour suppressor capable of efficiently inducing apoptosis

The ING1b protein is a type-II tumour suppressor and stoichiometric member of the Sin3 histone deacetylase (HDAC) protein complex in which it acts to target HDAC activity to regulate chromatin structure. Altering ING1 levels by ectopic expression of ING1b in cancer cells promotes apoptosis, whereas...

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Detalles Bibliográficos
Autores principales: Boyko, A, Riabowol, K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979497/
https://www.ncbi.nlm.nih.gov/pubmed/27551477
http://dx.doi.org/10.1038/cddiscovery.2015.48

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979497/
https://www.ncbi.nlm.nih.gov/pubmed/27551477
http://dx.doi.org/10.1038/cddiscovery.2015.48

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