AMPK maintains energy homeostasis and survival in cancer cells via regulating p38/PGC-1α-mediated mitochondrial biogenesis

Cancer cells exhibit unique metabolic response and adaptation to the fluctuating microenvironment, yet molecular and biochemical events imprinting this phenomenon are unclear. Here, we show that metabolic homeostasis and adaptation to metabolic stress in cancer cells are primarily achieved by an int...

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Detalles Bibliográficos
Autores principales: Chaube, B, Malvi, P, Singh, S V, Mohammad, N, Viollet, B, Bhat, M K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979508/
https://www.ncbi.nlm.nih.gov/pubmed/27551487
http://dx.doi.org/10.1038/cddiscovery.2015.63

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979508/
https://www.ncbi.nlm.nih.gov/pubmed/27551487
http://dx.doi.org/10.1038/cddiscovery.2015.63

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