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Compact, Polyvalent Mannose Quantum Dots as Sensitive, Ratiometric FRET Probes for Multivalent Protein–Ligand Interactions

A highly efficient cap‐exchange approach for preparing compact, dense polyvalent mannose‐capped quantum dots (QDs) has been developed. The resulting QDs have been successfully used to probe multivalent interactions of HIV/Ebola receptors DC‐SIGN and DC‐SIGNR (collectively termed as DC‐SIGN/R) using...

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Detalles Bibliográficos
Autores principales: Guo, Yuan, Sakonsinsiri, Chadamas, Nehlmeier, Inga, Fascione, Martin A., Zhang, Haiyan, Wang, Weili, Pöhlmann, Stefan, Turnbull, W. Bruce, Zhou, Dejian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979658/
https://www.ncbi.nlm.nih.gov/pubmed/26990806
http://dx.doi.org/10.1002/anie.201600593