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Quantitative proteomics and network analysis of SSA1 and SSB1 deletion mutants reveals robustness of chaperone HSP70 network in Saccharomyces cerevisiae

Molecular chaperones play an important role in protein homeostasis and the cellular response to stress. In particular, the HSP70 chaperones in yeast mediate a large volume of protein folding through transient associations with their substrates. This chaperone interaction network can be disturbed by...

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Detalles Bibliográficos
Autores principales: Jarnuczak, Andrew F., Eyers, Claire E., Schwartz, Jean‐Marc, Grant, Christopher M., Hubbard, Simon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979674/
https://www.ncbi.nlm.nih.gov/pubmed/25689132
http://dx.doi.org/10.1002/pmic.201400527