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Automated glycan assembly of a S. pneumoniae serotype 3 CPS antigen

Vaccines against S. pneumoniae, one of the most prevalent bacterial infections causing severe disease, rely on isolated capsular polysaccharide (CPS) that are conjugated to proteins. Such isolates contain a heterogeneous oligosaccharide mixture of different chain lengths and frame shifts. Access to...

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Detalles Bibliográficos
Autores principales: Weishaupt, Markus W, Matthies, Stefan, Hurevich, Mattan, Pereira, Claney L, Hahm, Heung Sik, Seeberger, Peter H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979738/
https://www.ncbi.nlm.nih.gov/pubmed/27559395
http://dx.doi.org/10.3762/bjoc.12.139