Beta-hydroxyphosphonate ribonucleoside analogues derived from 4-substituted-1,2,3-triazoles as IMP/GMP mimics: synthesis and biological evaluation

A series of seventeen β-hydroxyphosphonate ribonucleoside analogues containing 4-substituted-1,2,3-triazoles was synthesized and fully characterized. Such compounds were designed as potential inhibitors of the cytosolic 5’-nucleotidase II (cN-II), an enzyme involved in the regulation of purine nucle...

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Detalles Bibliográficos
Autores principales: Nguyen Van, Tai, Hospital, Audrey, Lionne, Corinne, Jordheim, Lars P, Dumontet, Charles, Périgaud, Christian, Chaloin, Laurent, Peyrottes, Suzanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2016
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979751/
https://www.ncbi.nlm.nih.gov/pubmed/27559400
http://dx.doi.org/10.3762/bjoc.12.144

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979751/
https://www.ncbi.nlm.nih.gov/pubmed/27559400
http://dx.doi.org/10.3762/bjoc.12.144

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