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Synergistic chiral iminium and palladium catalysis: Highly regio- and enantioselective [3 + 2] annulation reaction of 2-vinylcyclopropanes with enals
A cooperative catalytic strategy of chiral iminium catalysis by regioselective activation of the C=C bond in enals and a transition metal promoting to open the 2-vinylcyclopropanes for highly regio- and enantioselective [3 + 2] cycloaddition reaction of 2-vinylcyclopropanes with α,β-unsaturated alde...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Beilstein-Institut
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979765/ https://www.ncbi.nlm.nih.gov/pubmed/27559383 http://dx.doi.org/10.3762/bjoc.12.127 |
| _version_ | 1782447370115481600 |
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| author | Zhu, Haipan Du, Peile Li, Jianjun Liao, Ziyang Liu, Guohua Li, Hao Wang, Wei |
| author_facet | Zhu, Haipan Du, Peile Li, Jianjun Liao, Ziyang Liu, Guohua Li, Hao Wang, Wei |
| author_sort | Zhu, Haipan |
| collection | PubMed |
| description | A cooperative catalytic strategy of chiral iminium catalysis by regioselective activation of the C=C bond in enals and a transition metal promoting to open the 2-vinylcyclopropanes for highly regio- and enantioselective [3 + 2] cycloaddition reaction of 2-vinylcyclopropanes with α,β-unsaturated aldehydes has been developed. |
| format | Online Article Text |
| id | pubmed-4979765 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2016 |
| publisher | Beilstein-Institut |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-49797652016-08-24 Synergistic chiral iminium and palladium catalysis: Highly regio- and enantioselective [3 + 2] annulation reaction of 2-vinylcyclopropanes with enals Zhu, Haipan Du, Peile Li, Jianjun Liao, Ziyang Liu, Guohua Li, Hao Wang, Wei Beilstein J Org Chem Full Research Paper A cooperative catalytic strategy of chiral iminium catalysis by regioselective activation of the C=C bond in enals and a transition metal promoting to open the 2-vinylcyclopropanes for highly regio- and enantioselective [3 + 2] cycloaddition reaction of 2-vinylcyclopropanes with α,β-unsaturated aldehydes has been developed. Beilstein-Institut 2016-06-29 /pmc/articles/PMC4979765/ /pubmed/27559383 http://dx.doi.org/10.3762/bjoc.12.127 Text en Copyright © 2016, Zhu et al. https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms) |
| spellingShingle | Full Research Paper Zhu, Haipan Du, Peile Li, Jianjun Liao, Ziyang Liu, Guohua Li, Hao Wang, Wei Synergistic chiral iminium and palladium catalysis: Highly regio- and enantioselective [3 + 2] annulation reaction of 2-vinylcyclopropanes with enals |
| title | Synergistic chiral iminium and palladium catalysis: Highly regio- and enantioselective [3 + 2] annulation reaction of 2-vinylcyclopropanes with enals |
| title_full | Synergistic chiral iminium and palladium catalysis: Highly regio- and enantioselective [3 + 2] annulation reaction of 2-vinylcyclopropanes with enals |
| title_fullStr | Synergistic chiral iminium and palladium catalysis: Highly regio- and enantioselective [3 + 2] annulation reaction of 2-vinylcyclopropanes with enals |
| title_full_unstemmed | Synergistic chiral iminium and palladium catalysis: Highly regio- and enantioselective [3 + 2] annulation reaction of 2-vinylcyclopropanes with enals |
| title_short | Synergistic chiral iminium and palladium catalysis: Highly regio- and enantioselective [3 + 2] annulation reaction of 2-vinylcyclopropanes with enals |
| title_sort | synergistic chiral iminium and palladium catalysis: highly regio- and enantioselective [3 + 2] annulation reaction of 2-vinylcyclopropanes with enals |
| topic | Full Research Paper |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979765/ https://www.ncbi.nlm.nih.gov/pubmed/27559383 http://dx.doi.org/10.3762/bjoc.12.127 |
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