The EIMS fragmentation mechanisms of the sesquiterpenes corvol ethers A and B, epi-cubebol and isodauc-8-en-11-ol

Farnesyl diphosphate (FPP) and all fifteen positional isomers of ((13)C(1))FPP were enzymatically converted by the bacterial terpene cyclases corvol ether synthase from Kitasatospora setae, the epi-cubebol synthase from Streptosporangium roseum, and the isodauc-8-en-11-ol synthase from Streptomyces...

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Detalles Bibliográficos
Autores principales: Rabe, Patrick, Dickschat, Jeroen S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2016
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979868/
https://www.ncbi.nlm.nih.gov/pubmed/27559388
http://dx.doi.org/10.3762/bjoc.12.132
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author Rabe, Patrick
Dickschat, Jeroen S
author_facet Rabe, Patrick
Dickschat, Jeroen S
author_sort Rabe, Patrick
collection PubMed
description Farnesyl diphosphate (FPP) and all fifteen positional isomers of ((13)C(1))FPP were enzymatically converted by the bacterial terpene cyclases corvol ether synthase from Kitasatospora setae, the epi-cubebol synthase from Streptosporangium roseum, and the isodauc-8-en-11-ol synthase from Streptomyces venezuelae. The enzyme products were analysed by GC–MS and GC–QTOF MS(2) and the obtained data were used to delineate the EIMS fragmentation mechanisms of the two sesquiterpene ethers corvol ethers A and B, and the sesquiterpene alcohols epi-cubebol and isodauc-8-en-11-ol.
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spelling pubmed-49798682016-08-24 The EIMS fragmentation mechanisms of the sesquiterpenes corvol ethers A and B, epi-cubebol and isodauc-8-en-11-ol Rabe, Patrick Dickschat, Jeroen S Beilstein J Org Chem Full Research Paper Farnesyl diphosphate (FPP) and all fifteen positional isomers of ((13)C(1))FPP were enzymatically converted by the bacterial terpene cyclases corvol ether synthase from Kitasatospora setae, the epi-cubebol synthase from Streptosporangium roseum, and the isodauc-8-en-11-ol synthase from Streptomyces venezuelae. The enzyme products were analysed by GC–MS and GC–QTOF MS(2) and the obtained data were used to delineate the EIMS fragmentation mechanisms of the two sesquiterpene ethers corvol ethers A and B, and the sesquiterpene alcohols epi-cubebol and isodauc-8-en-11-ol. Beilstein-Institut 2016-07-05 /pmc/articles/PMC4979868/ /pubmed/27559388 http://dx.doi.org/10.3762/bjoc.12.132 Text en Copyright © 2016, Rabe and Dickschat https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Full Research Paper
Rabe, Patrick
Dickschat, Jeroen S
The EIMS fragmentation mechanisms of the sesquiterpenes corvol ethers A and B, epi-cubebol and isodauc-8-en-11-ol
title The EIMS fragmentation mechanisms of the sesquiterpenes corvol ethers A and B, epi-cubebol and isodauc-8-en-11-ol
title_full The EIMS fragmentation mechanisms of the sesquiterpenes corvol ethers A and B, epi-cubebol and isodauc-8-en-11-ol
title_fullStr The EIMS fragmentation mechanisms of the sesquiterpenes corvol ethers A and B, epi-cubebol and isodauc-8-en-11-ol
title_full_unstemmed The EIMS fragmentation mechanisms of the sesquiterpenes corvol ethers A and B, epi-cubebol and isodauc-8-en-11-ol
title_short The EIMS fragmentation mechanisms of the sesquiterpenes corvol ethers A and B, epi-cubebol and isodauc-8-en-11-ol
title_sort eims fragmentation mechanisms of the sesquiterpenes corvol ethers a and b, epi-cubebol and isodauc-8-en-11-ol
topic Full Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979868/
https://www.ncbi.nlm.nih.gov/pubmed/27559388
http://dx.doi.org/10.3762/bjoc.12.132
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