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Enantioselective addition of diphenyl phosphonate to ketimines derived from isatins catalyzed by binaphthyl-modified organocatalysts

Chiral binaphthyl-modified squaramide-catalyzed enantioselective addition of diphenyl phosphonate to ketimines derived from isatins has been achieved. This method affords practical and efficient access to chiral 3-amino-3-phosphonyl-substituted oxindole derivatives in high yields with excellent enan...

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Detalles Bibliográficos
Autores principales: Jang, Hee Seung, Kim, Yubin, Kim, Dae Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979900/
https://www.ncbi.nlm.nih.gov/pubmed/27559405
http://dx.doi.org/10.3762/bjoc.12.149