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miR-6734 Up-Regulates p21 Gene Expression and Induces Cell Cycle Arrest and Apoptosis in Colon Cancer Cells

Recently, microRNAs have been implicated in the regulation of gene expression in terms of both gene silencing and gene activation. Here, we investigated the effects of miR-6734, which has a sequence homology with a specific region of p21(WAF1/CIP1) (p21) promoter, on cancer cell growth and the mecha...

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Detalles Bibliográficos
Autores principales: Kang, Moo Rim, Park, Ki Hwan, Yang, Jeong-Ook, Lee, Chang Woo, Oh, Soo Jin, Yun, Jieun, Lee, Myeong Youl, Han, Sang-Bae, Kang, Jong Soon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979902/
https://www.ncbi.nlm.nih.gov/pubmed/27509128
http://dx.doi.org/10.1371/journal.pone.0160961