PKC activation sensitizes basal-like breast cancer cell lines to Smac mimetics

There is a need for novel strategies to initiate cancer cell death. One approach is the use of Smac mimetics, which antagonize inhibitor of apoptosis proteins (IAPs). Recent studies have shown that combinations of Smac mimetics such as LBW242 or LCL161 in combination with chemotherapeutic agents inc...

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Detalles Bibliográficos
Autores principales: Cornmark, L, Holmgren, C, Masoumi, K, Larsson, C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979953/
https://www.ncbi.nlm.nih.gov/pubmed/27551497
http://dx.doi.org/10.1038/cddiscovery.2016.2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979953/
https://www.ncbi.nlm.nih.gov/pubmed/27551497
http://dx.doi.org/10.1038/cddiscovery.2016.2

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