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Mannose 6-Phosphate Receptor Is Reduced in -Synuclein Overexpressing Models of Parkinsons Disease

Increasing evidence points to defects in autophagy as a common denominator in most neurodegenerative conditions. Progressive functional decline in the autophagy-lysosomal pathway (ALP) occurs with age, and the consequent impairment in protein processing capacity has been associated with a higher ris...

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Detalles Bibliográficos
Autores principales: Matrone, Carmela, Dzamko, Nicolas, Madsen, Peder, Nyegaard, Mette, Pohlmann, Regina, Søndergaard, Rikke V., Lassen, Louise B., Andresen, Thomas L., Halliday, Glenda M., Jensen, Poul Henning, Nielsen, Morten S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979956/
https://www.ncbi.nlm.nih.gov/pubmed/27509067
http://dx.doi.org/10.1371/journal.pone.0160501