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Overexpression of Hypo-Phosphorylated IκBβ at Ser313 Protects the Heart against Sepsis
IκBβis an inhibitor of nuclear factor kappa B(NF-κB) and participates in the cardiac response to sepsis. However, the role of the hypo-phosphorylated form of IκBβ at Ser313, which can be detected during sepsis, is unknown. Here, we examined the effects of IκBβ with a mutation at Ser313→Ala313 on car...
Autores principales: | Wang, Guang-Qing, Tang, Tao, Wang, Zhong-Shan, Liu, Ying-Ying, Wang, Li, Luo, Peng-Fei, Xia, Zhao-Fan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979969/ https://www.ncbi.nlm.nih.gov/pubmed/27508931 http://dx.doi.org/10.1371/journal.pone.0160860 |
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