Exercise Activates p53 and Negatively Regulates IGF-1 Pathway in Epidermis within a Skin Cancer Model

Exercise has been previously reported to lower cancer risk through reducing circulating IGF-1 and IGF-1-dependent signaling in a mouse skin cancer model. This study aims to investigate the underlying mechanisms by which exercise may down-regulate the IGF-1 pathway via p53 and p53-related regulators...

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Detalles Bibliográficos
Autores principales: Yu, Miao, King, Brenee, Ewert, Emily, Su, Xiaoyu, Mardiyati, Nur, Zhao, Zhihui, Wang, Weiqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979999/
https://www.ncbi.nlm.nih.gov/pubmed/27509024
http://dx.doi.org/10.1371/journal.pone.0160939

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979999/
https://www.ncbi.nlm.nih.gov/pubmed/27509024
http://dx.doi.org/10.1371/journal.pone.0160939

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