The 4p16.3 Parkinson Disease Risk Locus Is Associated with GAK Expression and Genes Involved with the Synaptic Vesicle Membrane

Genome-wide association studies (GWAS) have identified the GAK/DGKQ/IDUA region on 4p16.3 among the top three risk loci for Parkinson’s disease (PD), but the specific gene and risk mechanism are unclear. Here, we report transcripts containing the 3’ clathrin-binding domain of GAK identified by RNA d...

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Detalles Bibliográficos
Autores principales: Nagle, Michael W., Latourelle, Jeanne C., Labadorf, Adam, Dumitriu, Alexandra, Hadzi, Tiffany C., Beach, Thomas G., Myers, Richard H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980018/
https://www.ncbi.nlm.nih.gov/pubmed/27508417
http://dx.doi.org/10.1371/journal.pone.0160925

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980018/
https://www.ncbi.nlm.nih.gov/pubmed/27508417
http://dx.doi.org/10.1371/journal.pone.0160925

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