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Netrin-1 Reduces Monocyte and Macrophage Chemotaxis towards the Complement Component C5a

Netrin-1, acting at its cognate receptor UNC5b, has been previously demonstrated to inhibit CC chemokine-induced immune cell migration. In line with this, we found that netrin-1 was able to inhibit CCL2-induced migration of bone marrow derived macrophages (BMDMs). However, whether netrin-1 is capabl...

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Detalles Bibliográficos
Autores principales: Taylor, Lewis, Brodermann, Maximillian Hugo, McCaffary, David, Iqbal, Asif Jilani, Greaves, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980032/
https://www.ncbi.nlm.nih.gov/pubmed/27509208
http://dx.doi.org/10.1371/journal.pone.0160685