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Lipophosphoglycans from Leishmania amazonensis Strains Display Immunomodulatory Properties via TLR4 and Do Not Affect Sand Fly Infection

The immunomodulatory properties of lipophosphoglycans (LPG) from New World species of Leishmania have been assessed in Leishmania infantum and Leishmania braziliensis, the causative agents of visceral and cutaneous leishmaniasis, respectively. This glycoconjugate is highly polymorphic among species...

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Detalles Bibliográficos
Autores principales: Nogueira, Paula M., Assis, Rafael R., Torrecilhas, Ana C., Saraiva, Elvira M., Pessoa, Natália L., Campos, Marco A., Marialva, Eric F., Ríos-Velasquez, Cláudia M., Pessoa, Felipe A., Secundino, Nágila F., Rugani, Jerônimo N., Nieves, Elsa, Turco, Salvatore J., Melo, Maria N., Soares, Rodrigo P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980043/
https://www.ncbi.nlm.nih.gov/pubmed/27508930
http://dx.doi.org/10.1371/journal.pntd.0004848