Differential effects of AMPK agonists on cell growth and metabolism

As a sensor of cellular energy status, the AMP-activated protein kinase (AMPK) is believed to act in opposition to the metabolic phenotypes favored by proliferating tumor cells. Consequently, compounds known to activate AMPK have been proposed as cancer therapeutics. However, the extent to which the...

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Detalles Bibliográficos
Autores principales: Vincent, Emma E., Coelho, Paula P., Blagih, Julianna, Griss, Takla, Viollet, Benoit, Jones, Russell G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980123/
https://www.ncbi.nlm.nih.gov/pubmed/25241895
http://dx.doi.org/10.1038/onc.2014.301

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980123/
https://www.ncbi.nlm.nih.gov/pubmed/25241895
http://dx.doi.org/10.1038/onc.2014.301

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