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A Naturally-Occurring Transcript Variant of MARCO Reveals the SRCR Domain is Critical for Function

Macrophage receptor with collagenous structure (MARCO) is a Class A Scavenger Receptor (cA-SR) that recognizes and phagocytoses of a wide variety of pathogens. Most cA-SRs that contain a C-terminal Scavenger Receptor Cysteine Rich (SRCR) domain use the proximal collagenous domain to bind ligands. In...

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Detalles Bibliográficos
Autores principales: Novakowski, Kyle E., Huynh, Angela, Han, SeongJun, Dorrington, Michael G., Yin, Charles, Tu, Zhongyuan, Pelka, Peter, Whyte, Peter, Guarné, Alba, Sakamoto, Kaori, Bowdish, Dawn M.E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980223/
https://www.ncbi.nlm.nih.gov/pubmed/26888252
http://dx.doi.org/10.1038/icb.2016.20