CD47 blocking antibodies restore phagocytosis and prevent atherosclerosis

Atherosclerosis is the disease process underlying heart attack and stroke(1). Advanced lesions at risk for rupture are characterized by the pathological accumulation of diseased vascular cells and apoptotic cellular debris(2). Why these cells are not cleared remains unknown(3). Here we show that ath...

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Detalles Bibliográficos
Autores principales: Kojima, Yoko, Volkmer, Jens-Peter, McKenna, Kelly, Civelek, Mete, Lusis, A. Jake, Miller, Clint, Direnzo, Daniel, Nanda, Vivek, Ye, Jianqin, Connolly, Andrew, Schadt, Eric, Quertermous, Thomas, Betancur, Paola, Maegdefessel, Lars, Perisic, Ljubica, Hedin, Ulf, Weissman, Irv, Leeper, Nicholas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980260/
https://www.ncbi.nlm.nih.gov/pubmed/27437576
http://dx.doi.org/10.1038/nature18935

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980260/
https://www.ncbi.nlm.nih.gov/pubmed/27437576
http://dx.doi.org/10.1038/nature18935

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