Treatment with Oxidized Phospholipids Directly Inhibits Nonalcoholic Steatohepatitis and Liver Fibrosis Without Affecting Steatosis

BACKGROUND AND AIMS: Previous studies demonstrated that toll-like receptors 4 and 2 (TLR-4 and TLR-2), which are expressed on liver-resident Kupffer, hepatic stellate cells, and circulating monocytes, play a role in nonalcoholic fatty liver disease. Lecinoxoids are oxidized phospholipids that antago...

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Detalles Bibliográficos
Autores principales: Mendel, Itzhak, Yacov, Niva, Shoham, Anat, Ishai, Eti, Breitbart, Eyal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980417/
https://www.ncbi.nlm.nih.gov/pubmed/27074921
http://dx.doi.org/10.1007/s10620-016-4159-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980417/
https://www.ncbi.nlm.nih.gov/pubmed/27074921
http://dx.doi.org/10.1007/s10620-016-4159-5

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