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Ctf4 Is a Hub in the Eukaryotic Replisome that Links Multiple CIP-Box Proteins to the CMG Helicase

Replisome assembly at eukaryotic replication forks connects the DNA helicase to DNA polymerases and many other factors. The helicase binds the leading-strand polymerase directly, but is connected to the Pol α lagging-strand polymerase by the trimeric adaptor Ctf4. Here, we identify new Ctf4 partners...

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Detalles Bibliográficos
Autores principales: Villa, Fabrizio, Simon, Aline C., Ortiz Bazan, Maria Angeles, Kilkenny, Mairi L., Wirthensohn, David, Wightman, Mel, Matak-Vinkovíc, Dijana, Pellegrini, Luca, Labib, Karim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980431/
https://www.ncbi.nlm.nih.gov/pubmed/27397685
http://dx.doi.org/10.1016/j.molcel.2016.06.009