A genome-wide screening uncovers the role of CCAR2 as an antagonist of DNA end resection

There are two major and alternative pathways to repair DNA double-strand breaks: non-homologous end-joining and homologous recombination. Here we identify and characterize novel factors involved in choosing between these pathways; in this study we took advantage of the SeeSaw Reporter, in which the...

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Detalles Bibliográficos
Autores principales: López-Saavedra, Ana, Gómez-Cabello, Daniel, Domínguez-Sánchez, María Salud, Mejías-Navarro, Fernando, Fernández-Ávila, María Jesús, Dinant, Christoffel, Martínez-Macías, María Isabel, Bartek, Jiri, Huertas, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980490/
https://www.ncbi.nlm.nih.gov/pubmed/27503537
http://dx.doi.org/10.1038/ncomms12364

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980490/
https://www.ncbi.nlm.nih.gov/pubmed/27503537
http://dx.doi.org/10.1038/ncomms12364

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