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Structural Basis for Plexin Activation and Regulation

Class A plexins (PlxnAs) act as semaphorin receptors and control diverse aspects of nervous system development and plasticity, ranging from axon guidance and neuron migration to synaptic organization. PlxnA signaling requires cytoplasmic domain dimerization, but extracellular regulation and activati...

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Detalles Bibliográficos
Autores principales: Kong, Youxin, Janssen, Bert J.C., Malinauskas, Tomas, Vangoor, Vamshidhar R., Coles, Charlotte H., Kaufmann, Rainer, Ni, Tao, Gilbert, Robert J.C., Padilla-Parra, Sergi, Pasterkamp, R. Jeroen, Jones, E. Yvonne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980550/
https://www.ncbi.nlm.nih.gov/pubmed/27397516
http://dx.doi.org/10.1016/j.neuron.2016.06.018