Long-term in vitro maintenance of clonal abundance and leukaemia-initiating potential in acute lymphoblastic leukaemia

Lack of suitable in vitro culture conditions for primary acute lymphoblastic leukaemia (ALL) cells severely impairs their experimental accessibility and the testing of new drugs on cell material reflecting clonal heterogeneity in patients. We show that Nestin-positive human mesenchymal stem cells (M...

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Detalles Bibliográficos
Autores principales: Pal, D, Blair, H J, Elder, A, Dormon, K, Rennie, K J, Coleman, D J L, Weiland, J, Rankin, K S, Filby, A, Heidenreich, O, Vormoor, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980562/
https://www.ncbi.nlm.nih.gov/pubmed/27109511
http://dx.doi.org/10.1038/leu.2016.79

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980562/
https://www.ncbi.nlm.nih.gov/pubmed/27109511
http://dx.doi.org/10.1038/leu.2016.79

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