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Leucine Zipper-bearing Kinase promotes axon growth in mammalian central nervous system neurons

Leucine Zipper-bearing Kinase (LZK/MAP3K13) is a member of the mixed lineage kinase family with high sequence identity to Dual Leucine Zipper Kinase (DLK/MAP3K12). While DLK is established as a key regulator of axonal responses to injury, the role of LZK in mammalian neurons is poorly understood. By...

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Detalles Bibliográficos
Autores principales: Chen, Meifan, Geoffroy, Cédric G., Wong, Hetty N., Tress, Oliver, Nguyen, Mallorie T., Holzman, Lawrence B., Jin, Yishi, Zheng, Binhai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980599/
https://www.ncbi.nlm.nih.gov/pubmed/27511108
http://dx.doi.org/10.1038/srep31482