CD14/TLR4 priming potentially recalibrates and exerts anti-tumor efficacy in tumor associated macrophages in a mouse model of pancreatic carcinoma

Pancreatic cancer is the fourth major cause of cancer related deaths in the world and 5 year survival is below 5%. Among various tumor directed therapies, stimulation of Toll-like receptors (TLR) has shown promising effects in various tumor models. However, pancreatic cancer cells frequently express...

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Detalles Bibliográficos
Autores principales: Prakash, Hridayesh, Nadella, Vinod, Singh, Sandhya, Schmitz-Winnenthal, Hubertus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980608/
https://www.ncbi.nlm.nih.gov/pubmed/27511884
http://dx.doi.org/10.1038/srep31490

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980608/
https://www.ncbi.nlm.nih.gov/pubmed/27511884
http://dx.doi.org/10.1038/srep31490

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