Cargando…
CD14/TLR4 priming potentially recalibrates and exerts anti-tumor efficacy in tumor associated macrophages in a mouse model of pancreatic carcinoma
Pancreatic cancer is the fourth major cause of cancer related deaths in the world and 5 year survival is below 5%. Among various tumor directed therapies, stimulation of Toll-like receptors (TLR) has shown promising effects in various tumor models. However, pancreatic cancer cells frequently express...
Autores principales: | Prakash, Hridayesh, Nadella, Vinod, Singh, Sandhya, Schmitz-Winnenthal, Hubertus |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980608/ https://www.ncbi.nlm.nih.gov/pubmed/27511884 http://dx.doi.org/10.1038/srep31490 |
Ejemplares similares
-
Emerging neo adjuvants for harnessing therapeutic potential of M1 tumor associated macrophages (TAM) against solid tumors: Enusage of plasticity
por: Nadella, Vinod, et al.
Publicado: (2020) -
Podophyllotoxin and Rutin Modulate M1 (iNOS+) Macrophages and Mitigate Lethal Radiation (LR) Induced Inflammatory Responses in Mice
por: Nadella, Vinod, et al.
Publicado: (2019) -
Sphingosine-1-Phosphate (S-1P) Promotes Differentiation of Naive Macrophages and Enhances Protective Immunity Against Mycobacterium tuberculosis
por: Nadella, Vinod, et al.
Publicado: (2020) -
Inhibitors of Apoptosis Protein Antagonists (Smac Mimetic Compounds) Control Polarization of Macrophages during Microbial Challenge and Sterile Inflammatory Responses
por: Nadella, Vinod, et al.
Publicado: (2018) -
A mechanistic role for the chromatin modulator, NAP1L1, in pancreatic neuroendocrine neoplasm proliferation and metastases
por: Schimmack, Simon, et al.
Publicado: (2014)