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Inhibition of CDK9 as a therapeutic strategy for inflammatory arthritis

Rheumatoid arthritis is characterised by synovial inflammation and proliferation of fibroblast-like synoviocytes. The induction of apoptosis has long been proposed as a target for proliferative autoimmune diseases, and has further been shown to act as a successful treatment of experimental models of...

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Detalles Bibliográficos
Autores principales: Hellvard, Annelie, Zeitlmann, Lutz, Heiser, Ulrich, Kehlen, Astrid, Niestroj, André, Demuth, Hans-Ulrich, Koziel, Joanna, Delaleu, Nicolas, Jan Potempa, Mydel, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980610/
https://www.ncbi.nlm.nih.gov/pubmed/27511630
http://dx.doi.org/10.1038/srep31441