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Fibroproliferative response to urothelial failure obliterates the ureter lumen in a mouse model of prenatal congenital obstructive nephropathy

Congenital obstructive nephropathy (CON) is the most prevalent cause of pediatric chronic kidney disease and end-stage renal disease. The ureteropelvic junction (UPJ) region, where the renal pelvis transitions to the ureter, is the most commonly obstructed site in CON. The underlying causes of conge...

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Detalles Bibliográficos
Autores principales: Lee, Amanda J., Polgar, Noemi, Napoli, Josephine A., Lui, Vanessa H., Tamashiro, Kadee-Kalia, Fujimoto, Brent A., Thompson, Karen S., Fogelgren, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980620/
https://www.ncbi.nlm.nih.gov/pubmed/27511831
http://dx.doi.org/10.1038/srep31137