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Fibroproliferative response to urothelial failure obliterates the ureter lumen in a mouse model of prenatal congenital obstructive nephropathy
Congenital obstructive nephropathy (CON) is the most prevalent cause of pediatric chronic kidney disease and end-stage renal disease. The ureteropelvic junction (UPJ) region, where the renal pelvis transitions to the ureter, is the most commonly obstructed site in CON. The underlying causes of conge...
Autores principales: | Lee, Amanda J., Polgar, Noemi, Napoli, Josephine A., Lui, Vanessa H., Tamashiro, Kadee-Kalia, Fujimoto, Brent A., Thompson, Karen S., Fogelgren, Ben |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980620/ https://www.ncbi.nlm.nih.gov/pubmed/27511831 http://dx.doi.org/10.1038/srep31137 |
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